Mutagenesis in Medicine
Early Cancer Institute, University of Cambridge

Shadi Basyuni

Clinical Research Fellow

I am an academic specialty trainee in oral and maxillo-facial surgery having been awarded the 2022 Royal College of Surgeons (RCS) Research Fellowship. I am committed to pursuing excellence in a career as an academic surgeon. I am motivated by the pursuit of scientific knowledge to improve our understanding of head & neck (H&N) cancer and outcomes for patients, as well as my career goal to establish an academic grounding more broadly in maxillo-facial surgery.

Working under the mentorship of Prof. Richard Shaw and Mr Andrew Schache (Liverpool Head & Neck Centre, University of Liverpool) over the last several years has allowed me to develop a particular research interest in oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) with a view of early detection and prevention. My current work is focussing on exploring the multi-omic determinants of malignant transformation in oral epithelial dysplasia and benefits from a supervisory collaboration between Prof. Serena Nik-Zainal and the Liverpool Head & Neck Centre.

Published Works

  • Basyuni, S., Sharma, V., Santhanam, V., & Ferro, A. (2015). Fatal thalamic abscess secondary to dental infection. BMJ case reports, 2015, bcr2015212589. https://doi.org/10.1136/bcr-2015-212589
  • Basyuni, S., & Quinnell, T. (2017). Autocannibalism induced by obstructive sleep apnea. Sleep medicine, 37, 72–73. https://doi.org/10.1016/j.sleep.2017.01.017
  • Ferro, A., Basyuni, S., Brassett, C., & Santhanam, V. (2017). Study of anatomical variations of the zygomaticofacial foramen and calculation of reliable reference points for operation. The British journal of oral & maxillofacial surgery, 55(10), 1035–1041. https://doi.org/10.1016/j.bjoms.2017.10.016
  • Basyuni, S., Barabas, M., & Quinnell, T. (2018). An update on mandibular advancement devices for the treatment of obstructive sleep apnoea hypopnoea syndrome. Journal of thoracic disease, 10(Suppl 1), S48–S56. https://doi.org/10.21037/jtd.2017.12.18
  • Alhassani, M., Santhanam, V., & Basyuni, S. (2018). Oral superficial haemosiderotic lymphovascular malformation: a rare presentation. BMJ case reports, 2018, bcr2017223043. https://doi.org/10.1136/bcr-2017-223043
  • Kent, S., Hennedige, A., McDonald, C., Henry, A., Dawoud, B., Kulkarni, R., Logan, G., Gilbert, K., Exely, R., Basyuni, S., Kyzas, P., Morrison, R., & McCaul, J. (2019). Systematic review of the role of corticosteroids in cervicofacial infections. The British journal of oral & maxillofacial surgery, 57(3), 196–206. https://doi.org/10.1016/j.bjoms.2019.01.010
  • Solanki, K., Basyuni, S., Zarringhalam, P., Nugent, G., Douglas, J., Rowe, A., & Magennis, P. (2019). Junior Trainees Group (JTG) of the British Association of Oral and Maxillofacial Surgeons (BAOMS) conference 2018: overview of the conference and analysis of delegates' feedback. The British journal of oral & maxillofacial surgery, 57(10), 1025–1031. https://doi.org/10.1016/j.bjoms.2019.08.027
  • Basyuni, S., Ferro, A., Santhanam, V., Birch, M., & McCaskie, A. (2020). Systematic scoping review of mandibular bone tissue engineering. The British journal of oral & maxillofacial surgery, 58(6), 632–642. https://doi.org/10.1016/j.bjoms.2020.03.016
  • Zhang, R., Lee, C. W., Basyuni, S., & Santhanam, V. (2020). Mandibular swelling as the initial presentation for renal cell carcinoma: A case report. International journal of surgery case reports, 70, 96–100. https://doi.org/10.1016/j.ijscr.2020.04.061
  • Jenkyn, I., Patel, K., Jenkyn, C., Basyuni, S., Talukder, S., & Cameron, M. (2021). Analysis of the frequency of bacteraemia of dental origin implicated in infective endocarditis in patients requiring valve surgery. The British journal of oral & maxillofacial surgery, 59(3), 329–334. https://doi.org/10.1016/j.bjoms.2020.08.095
  • Surman, K., Duffy, N., Anwar, Z., Basyuni, S., & Santhanam, V. (2021). Submental intubation in craniomaxillofacial surgery. Anaesthesia, critical care & pain medicine, 40(1), 100796. https://doi.org/10.1016/j.accpm.2020.100796
  • Henry, A., Dawoud, B., Kent, S., McDonald, C., Logan, G., Hennedige, A., Exely, R., Regan, A., Kulkarni, R., Gilbert, K., Basyuni, S., Young, D., Kyzas, P., Morrison, R., McCaul, J., & List of collaborators who participated in the Cervicofacial Infection Study (2021). Clinical features and presentation of cervicofacial infection: a Maxillofacial Trainee Research Collaborative (MTReC) study. The British journal of oral & maxillofacial surgery, 59(4), 433–438. https://doi.org/10.1016/j.bjoms.2020.08.102
  • Kapur, M., Shah, R. A., Ferro, A., Basyuni, S., Brassett, C., & Santhanam, V. (2021). Sexual dimorphism and geographical variance: their impact on the reliability of the antilingula as a landmark in human mandibular surgery. The British journal of oral & maxillofacial surgery, 59(8), 898–904. https://doi.org/10.1016/j.bjoms.2020.08.024
  • Ferro, A., Basyuni, S., Bosley, R., & Santhanam, V. (2021). A predictive model for swallowing dysfunction after oral cancer resection. The British journal of oral & maxillofacial surgery, 59(9), 1043–1049. https://doi.org/10.1016/j.bjoms.2021.01.007
  • Basyuni, S., Nugent, G., Ferro, A., Barker, E., Reddin, I., Jones, O., Lechner, M., O'Leary, B., Jones, T., Masterson, L., Fenton, T., & Schache, A. (2022). Value of p53 sequencing in the prognostication of head and neck cancer: a systematic review and meta-analysis. Scientific reports, 12(1), 20776. https://doi.org/10.1038/s41598-022-25291-2
  • Chu, J., Basyuni, S., Moore, S., Ferro, A., Chang, C., Patel, K., Jeremiah, H., Brassett, C., & Santhanam, V. (2023). A Novel Cephalometric Approach Aiming to Quantify a Normal Range of Bony Chin Protrusion. Journal of maxillofacial and oral surgery, 22(1), 226–231. https://doi.org/10.1007/s12663-022-01784-5

Contact Us

Prof. Serena Nik-Zainal
Early Cancer Institute
University of Cambridge
Hutchison Research Centre
Box 197
Cambridge Biomedical Campus
Cambridge
United Kingdom
CB2 0XZ

sn206@cam.ac.uk