Physiology of Mutagenesis
University of Cambridge & MRC Cancer Unit

Dr. Gene CC Koh

Research associate

Gene obtained his MSc from Universität Heidelberg with a major in Systems Biology and trained in mass spectrometry-based proteomics under Ruedi Aebersold at ETH Zürich. Bored of the snow in Switzerland, he then traded it for the rain in the UK to pursue his PhD at the Wellcome Trust Sanger Institute, immersing in the world of genomics and getting to work out, using experimental systems, how mutational processes leave characteristic patterns in the genome. Particularly, he’s passionate about combining molecular biology techniques, such as CRISPR/Cas9, with Omic technologies to understand how DNA damage and repair processes jointly shape the mutational signatures in human cancers. When he’s not editing cells in the lab, he’s likely wrestling with R in front of his computer, trying to make sense of a piece of code. Get in touch should you wish to brainstorm project ideas or just to chitchat with him 🙂