Physiology of Mutagenesis
University of Cambridge & MRC Cancer Unit

Dr. Gene CC Koh

Research Associate

Gene obtained his MSc from Universität Heidelberg with a major in Systems Biology and trained in mass spectrometry-based proteomics under Ruedi Aebersold at ETH Zürich. Bored of the snow in Switzerland, he then traded it for the rain in the UK to pursue his PhD at the Wellcome Trust Sanger Institute. His work focuses on DNA damage, mutagenesis, and Cancer. He uses experimental systems to delineate how mutational processes leave characteristic patterns in the genome. Particularly, he’s passionate about combining molecular biology techniques, such as CRISPR/Cas9, with ‘omic’ technologies to understand how DNA damage and repair processes jointly shape the mutational landscape in human cancers. When he’s not editing cells in the lab, he’s likely wrestling with a piece of R code in front of his computer. Get in touch should you wish to brainstorm project ideas or just to chitchat (: